Inflexible: it does what it does well, but if you need more your out of luck for the most part. Built in support for importing exporting excel, cvs, tab-formatted. Has some neat built in tricks like built in graphs, tab controls, web viewers. Changing field/database/script names after the fact is free. For the most part, drag and drop programming. Anyone with access can edit the program. There are many plugins available to extend functionality. Cross-platform (Mac OS X, Windows, iOS). Easy to deploy locally, turn on sharing and connect from another client. 
Here are the pros and cons of using Filemaker Pro vs PHP/MySQL/HTML in my experience. Comparing the two, they both have pros an cons. It's like you have MySQL, PHP, HTML and your editor put together in a GUI.
They're both in the same category of software, they're integrated programming environments. Calling Filemaker Pro, Access for the Mac is kind of like saying, Mac OS X is Windows for the Mac.
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